The Quadruple Marker Test is a safe, routine, and empowering screening test offered during your second trimester of pregnancy. It is not a diagnostic test. It measures four specific markers in your blood (AFP, HCG, Estriol, and Inhibin-A) and combines them with your age to calculate a personalized risk assessment for chromosomal conditions like Down syndrome and neural tube defects. A simple blood draw is all that is required. This test provides invaluable, early information, giving you and your doctor a clearer picture and empowering you to make the most informed decisions for your pregnancy journey.