If you're experiencing unexplained muscle weakness or pain, this test can provide a crucial answer. The Aldolase Serum test measures an enzyme found in high concentrations in your muscle and liver. When muscles are damaged, they release aldolase into the blood. This test is essential for diagnosing and monitoring inflammatory muscle diseases, such as polymyositis or dermatomyositis. This simple blood test helps your doctor determine if your symptoms are being caused by muscle inflammation, putting you on the right path to a solution.